Medications may be recommended for the treatment of facet-mediated pain. These typically include over-the-counter pain relievers such as anti-inflammatories or acetaminophen. Topical treatments such as heat or ice may be used. Physical therapy is often recommended and includes focus on postural correction, stretching, and strengthening. There is often a focus on strengthening the abdominal and low back muscles.

When conservative treatments are not helpful, a facet joint injection with corticosteroid or radiofrequency ablation may be recommended. These procedures are performed with fluoroscopic guidance with an X-ray machine. There are newer treatments being tried, including injection of platelet-rich plasma (PRP) and/or bone marrow concentrate. These newer treatments are considered experimental and are an out-of-pocket expense (not typically covered by medical insurance).