Carpal tunnel

Numbness, tingling, burning, or itching in the palm side of the hand and fingers, particularly the thumb, index, and middle fingers
Symptoms may initially occur at night when many people sleep with their wrists in bent positions, which increases carpal tunnel pressures. People with carpal tunnel syndrome often wake up at night with numb or tingling fingers and need to shake their hands to resolve the symptoms
Some people may report incoordination or difficulty holding and manipulating small objects like pens and tools
Symptoms may occur only with specific activities or wrist positions at first but may later become more constant
In long-standing or severe cases, the thumb muscles may shrink and become significantly weak

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